Image

Madison Keys vs Donna Vekic preview, head-to-head, odds, prediction & betting ideas

Match Details

Fixture: Madison Keys vs Donna Vekic

Date: Wednesday, March 1, 2026

Tournament: Credit One Charleston Open 2026

Round: Second Round

Category: WTA 500

Surface: Outdoor clay (green)

Venue: Credit One Stadium, Charleston, South Carolina, United States of America

Prize Money: $2,500,000

Live Telecast: USA – Tennis Channel | UK – Sky Sports | Canada – TSN


Madison Keys vs Donna Vekic preview

Madison Keys in action at the 2026 Miami Open (Source: Getty)Madison Keys in action at the 2026 Miami Open (Source: Getty)
Madison Keys in action at the 2026 Miami Open (Source: Getty)

Madison Keys and Donna Vekic are set to lock horns in a high-profile second-round clash at the 2026 Charleston Open.

Keys, a former World No. 5 currently ranked 18th, is the fifth seed in Charleston and will begin her campaign at the WTA 250 claycourt event with the second-round match against Vekic. Before arriving in South Carolina, the 31-year-old endured a disappointing ‘Sunshine Double’, suffering third-round losses at both the BNP Paribas Open in Indian Wells and the Miami Open.

Vekic, a former No. 17, is ranked at a lowly World No. 115 now, and needed to qualify for the main draw in Charleston. The Croat came back from a set down in the first round against Ajla Tomljanovic to take the contest 3-6, 6-1, 6-4. Previously, the 29-year-old lost to Jessica Pegula in the second round in Indian Wells and then failed to qualify for the main draw in Miami.


Madison Keys vs Donna Vekic head-to-head

Donna Vekic during a qualifying-round match at the 2026 Miami Open (Source: Getty)Donna Vekic during a qualifying-round match at the 2026 Miami Open (Source: Getty)
Donna Vekic during a qualifying-round match at the 2026 Miami Open (Source: Getty)

Keys leads the head-to-head against Vekic 4-1. The pair has so far faced each other three times on clay and all of them went the American’s way, that too in straight sets.


Madison Keys vs Donna Vekic odds

Player Name Moneyline Handicap Bets Total Games
Madison Keys -300 -4.5 (-105) Over 20.5 (-130)
Donna Vekic +225 +4.5 (-140) Under 20.5 (-110)

(Odds via BetMGM)


Madison Keys vs Donna Vekic prediction

Keys is the favourite to defeat Vekic in their upcoming second-round clash at the 2026 Charleston Open. Keys, the 2019 Charleston champion, should be confident going into the match considering her flawless head-to-head record against Vekic on clay.

While the Croatian showed resilience by rallying to beat Ajla Tomljanovic in the first round, she has struggled this season and recently fell out of the top 100. The American’s superior power and history on Charleston’s green clay make her the likely winner. Expect a straight-sets victory for Keys as she capitalizes on Vekić’s inconsistent second serve.

Pick: Keys to win in straight sets.


Madison Keys vs Donna Vekic betting tips

Tip 1: Previous high-stakes matches between these two, such as their 2025 Indian Wells fourth-round clash, have gone the distance, suggesting Vekic may fight to keep the game count high even if she loses.

Tip 2: There is value in the 2-0 scoreline.