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Flavio Cobolli vs Stan Wawrinka preview, head-to-head, odds, prediction, & betting ideas

Match Details

Fixture: (1) Flavio Cobolli vs Stan Wawrinka

Date: October 22, 2026

Tournament: Lyon Open

Round: Second Round (Round of 16)

Venue: LDLC Arena, Lyon, France

Category: ATP 250

Surface: Hard (Indoor)

Prize Money: €757,320

Live Telecast: USA – Tennis Channel | UK – Sky Sports | Canada – TSN Premium


Flavio Cobolli vs Stan Wawrinka preview

Top seed Flavio Cobolli will face off against Stan Wawrinka in the second round of the 2026 Lyon Open on Thursday.

Cobolli heads into the Lyon Open Round of 16 looking to make a strong start after receiving a bye in the opening round. The Italian has enjoyed some notable results this season, reaching the finals at Roland Garros, Munich and the semifinals in Cincinnati. However, his recent outings in Asia were less successful, with early exits at the China Open and Shanghai Masters. The top seed will be hoping to use the indoor conditions to his advantage as he begins his campaign in Lyon.

Wawrinka, meanwhile, booked his place in the second round with a hard-fought win over Martin Landaluce. The Swiss defeated the Spaniard 6-3, 6-7(2), 7-6(5), holding his nerve in the deciding-set tiebreak to progress. The victory marked a significant result for the veteran, who is nearing the end of his professional career. Wawrinka will now face a considerably tougher challenge against Cobolli as he looks to extend his run in Lyon.


Flavio Cobolli vs Stan Wawrinka head-to-head

Cobolli leads Stan Wawrinka 2-0 in their ATP Tour meetings. Cobolli won their first encounter at the 2024 Shanghai Masters, defeating Wawrinka in three sets before edging the Swiss in three sets again at the United Cup in January 2026.


Flavio Cobolli vs Stan Wawrinka odds

Player Moneyline Handicap Bets Total Games
Flavio Cobolli -275 -2.5 (-145) Over 22.5 (-130)
Stan Wawrinka +210 +2.5 (+100) Under 22.5 (-110)

(Odds via BetMGM)


Flavio Cobolli vs Stan Wawrinka prediction

Flavio Cobolli should have the upper hand in this matchup, with his higher ranking and stronger results throughout the season giving him the advantage. However, the Italian has struggled in recent hard-court tournaments, suffering early exits in Beijing and Shanghai. As the top seed in Lyon, he will be eager to put those disappointments behind him and make a convincing start to his campaign.

Wawrinka, meanwhile, will take confidence from his hard-fought opening-round victory over Martin Landaluce. The Swiss veteran showed that he can still compete in tight matches, but his recent results have been inconsistent. His powerful first serve and one-handed backhand could make him dangerous on the indoor hard courts, particularly if he can keep the points short and force Cobolli onto the defensive.

Cobolli has won both of their previous meetings, including a three-set battle at the United Cup in January. Although Wawrinka’s experience could make this a tricky encounter, Cobolli’s greater consistency over the season should help him manage the key moments. If he serves well and avoids allowing the veteran to dictate with his forehand, he should have enough to advance.

Pick: Cobolli to win in straight sets.


Flavio Cobolli vs Stan Wawrinka betting tips

Tip 1: The match will have at least 18 games.

Tip 2: Cobolli to win at least one set with a score of 6-4.

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Edited by Pritha Ghosh

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