The Chicago Cubs host the Cincinnati Reds at Wrigley Field on Tuesday, continuing their twelfth series of the 2026 MLB season. The Cubs ran out 5-4 winners in Monday’s series opener.
Let’s look at the odds, preview, prediction and best betting tips for the game.
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MLB: Chicago Cubs vs Cincinnati Reds odds
Money Line: Chicago Cubs (-168), Cincinnati Reds (+139)
Run Line: Chicago Cubs -1.5 (+129), Cincinnati Reds +1.5 (-156)
Total Runs: Over 8 (-115), Under 8 (-105)
Preview – Probable starting pitchers and lineups
Chicago Cubs probable starting pitcher: Jameson Taillon
Jameson Taillon gets the starting nod for the hosts. The righty comes into the game with a 2-1 record and a 4.41 ERA.
Chicago Cubs predicted lineup:
- 2B Nico Hoerner
- 1B Michael Busch
- 3B Alex Bregman
- OF Ian Happ
- DH Moises Ballesteros
- OF Michael Conforto
- C Miguel Amaya
- OF Pete Crow-Armstrong
- SS Dansby Swanson
Cincinnati Reds probable starting pitcher: Andrew Abbott
Andrew Abbott takes the mound for the visitors. The southpaw comes into the matchup with a 1-2 record and a 5.97 ERA.
Cincinnati Reds predicted lineup:
- OF TJ Friedl
- OF JJ Bleday
- SS Elly De La Cruz
- 1B Sal Stewart
- DH Nathaniel Lowe
- C Tyler Stephenson
- OF Spencer Steer
- 2B Matt McLain
- 3B Ke’Bryan Hayes
The Cubs will come into the game full of confidence after Monday’s win, and they should have enough in the tank to secure another important victory on Tuesday.
Prediction: Chicago Cubs 5, Cincinnati Reds 4
Betting Tips
The Cubs are strong at home and they should have more than enough talent in their ranks to secure another win on home turf, taking a 2-0 lead in the four-game series in the process.
Money Line: Chicago Cubs (-168)
Run Line: Cincinnati Reds +1.5 (-156)
Total Runs: Over 8 (-115)
Likely players to hit home runs: Ian Happ (Chicago Cubs), Seiya Suzuki (Chicago Cubs), Elly De La Cruz (Cincinnati Reds), Sal Stewart (Cincinnati Reds)
Edited by Raghav Mehta
