The Los Angeles Dodgers host the Cleveland Guardians at Dodger Stadium on Monday, starting their second series of the MLB regular season.
In their first series, the Dodgers swept the Arizona Diamondbacks, while the Guardians put in a solid performance on the road to split their opening series with the Seattle Mariners.
Let’s take a look at the odds, preview, prediction and best betting tips for this fixture.
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MLB: Los Angeles Dodgers vs Cleveland Guardians Odds
Money Line: Los Angeles Dodgers (-194), Cleveland Guardians (+159)
Run Line: Los Angeles Dodgers -1.5 (+109), Cleveland Guardians +1.5 (-131)
Total Runs: Over 8.5 (-122), Under 8.5 (+102)
Preview – Probable starting pitchers and lineups
Los Angeles Dodgers probable starting pitcher: Roki Sasaki
Roki Sasaki gets the nod to start this game for the Dodgers. Having sealed a sensational move to MLB last year, Sasaki’s first year as a starting pitcher did not go to plan, and he evnetually ended the year playing as the Dodgers’ closer in the playoffs. Fans will hope to see him fare better this time around.
Los Angeles Dodgers predicted lineup:
- DH Shohei Ohtani
- OF Kyle Tucker
- SS Mookie Betts
- 1B Freddie Freeman
- C Will Smith
- 3B Max Muncy
- OF Teoscar Hernandez
- OF Andy Pages
- 2B Miguel Rojas
Cleveland Guardians probable starting pitcher: Parker Messick
Parker Messick takes the mound for the Guardians. Having made his MLB debut in August 2025, Messick put in some solid performances, finishing the campaign with a 3-1 record, a 2.72 ERA and 38 strikeouts.
Cleveland Guardians predicted lineup:
- OF Steven Kwan
- OF Chase DeLauter
- 3B Jose Ramirez
- DH Kyle Manzardo
- C Bo Naylor
- 1B Rhys Hoskins
- OF Daniel Schneemann
- SS Gabriel Arias
- 2B Brayan Rocchio
The Guardians are tough to beat, as the Seattle Mariners learned first-hand, and they will be fancying their chances of staging an upset. However, taking on the Dodgers on the road is probably the toughest assignment in MLB at the moment. The hosts should have enough in the tank to prevail once again.
Prediction: Los Angeles Dodgers 7, Cleveland Guardians 2
Betting Tips
Playing at home and full of confidence after sweeping the Diamondbacks, the Dodgers should have no problems continuing their perfect start to the season.
Money Line: Los Angeles Dodgers (-194)
Run Line: Los Angeles Dodgers -1.5 (+109)
Total Runs: Over 8.5 (-122)
Likely players to hit home runs: Shohei Ohtani (Los Angeles Dodgers), Kyle Tucker (Los Angeles Dodgers), Jose Ramirez (Cleveland Guardians), Chase DeLauter (Cleveland Guardians)
Edited by Raghav Mehta
