Randy Moss asking for prayers for himself and his family … ’cause he says he’s been dealing with something internal — and apparently it’s affecting his eyes.

The NFL Hall of Famer took to his Instagram Sunday morning — while working alongside his cohosts on “Sunday NFL Countdown” … speaking to fans directly and telling them he’s been battling some sort of health issues recently.

Moss doesn’t go into detail about the exact issues … but, he asks all the “prayer warriors” to keep him and his family in their thoughts — so, it sounds fairly serious.

Randy then puts on a pair of sunglasses … saying if people see him wearing them on the show, it’s because of this issue he’s dealing with — not because he’s making a fashion choice.

RM ends the message on an uplifting note … telling fans not to worry ’cause he’s got a great team of doctors around him — before specifically telling men they need to get regular check-ups and blood work done.

Moss is one of the most dominant wide receivers ever … racking up 156 touchdown catches and more than 15k receiving yards across his 14-year career.